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Last updated: 1 Feb 2021

Best Enzyme Pet Stain Cleaners and Odor Eliminators (Review) in 2021

Top Pick
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Angry Orange Pet Stain and Odor Eliminator
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Best Odor Eliminator
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Rocco & Roxie Supply Pet Stain and Odor Eliminator
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Most Cleansing
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OUT! Pet Stain and Odor Eliminator
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Best Budget
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Simple Solution Pet Stain and Odor Eliminator
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Best Quality
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Amaziing Solutions Pet Stain and Odor Eliminator
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Best Multiple Uses
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BUBBAS ROWDY FRIENDS Pet Stain and Odor Eliminator
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Melissa Bartholomew
By Melissa Bartholomew
Published 7:14 am
Show contents
  • 1 Angry Orange Pet Stain and Odor Eliminator
  • 2 Rocco & Roxie Supply Pet Stain and Odor Eliminator
  • 3 OUT! Pet Stain and Odor Eliminator
  • 4 Simple Solution Pet Stain and Odor Eliminator
  • 5 Amaziing Solutions Pet Stain and Odor Eliminator
  • 6 BUBBAS ROWDY FRIENDS Pet Stain and Odor Eliminator

Enzyme cleaners are becoming popular among pet owners who want to go natural against stains and odors. Unlike traditional cleaners that contain potentially harmful chemicals, the amino acids in enzyme cleaners break down stains into more manageable substances before consuming odor-causing bacteria.

We’ve done an extensive background check on a variety of these products for you and came up with the best enzyme pet stain cleaners and odor eliminators in 2021. All the items target odor and stain removal from liquid and solid pet waste and can clean different surfaces.

Best Enzyme Pet Stain Cleaner and Odor Eliminator

1

Angry Orange Pet Stain and Odor Eliminator

– Top Pick
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THE SCOOP

You can make a gallon of solution using the 8-oz concentrate or four 32-oz spraying bottles using two tablespoons of the concentrate per bottle.This biodegradable and non-toxic product is made from oils extracted from orange peels, pineapple, and coconut. It can remove ammonia and methane-smelling animal odors from not just home indoor surfaces like beddings and mattresses, but also vehicle interiors, stables, barns, and animal shelters. It works on fabrics, hardwood, tiles, carpets, and grass.

Pros
  • Commercial grade odor remover
  • Works on various surfaces Money-saver
Cons
  • No sprayer
2

Rocco & Roxie Supply Pet Stain and Odor Eliminator

– Best Odor Eliminator
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THE SCOOP

Rocco & Roxie Professional Strength Stain & Odor Eliminator – Enzyme-Powered Pet Odor & Stain Remover for Dog and Cats Urine. This odor remover contains natural enzymatic bacteria, which are activated on contact. It’s chlorine-free, color-safe and safe to use around children and pets. It can be used on every surface.

Key Features

Rocco & Roxie Professional Strength Stain & Odor is strong enough to make old stains disappear within minutes. It also prevents pets from returning to the same spot to do their business. However, the fumes can be strong and require airing out the room after the formula is sprayed.

Pros
  • Works great on multiple surfaces
Cons
  • Must cover it with a towel and weight
3

OUT! Pet Stain and Odor Eliminator

– Most Cleansing
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THE SCOOP

OUT! Advanced Stain and Odor Remover | Pet Stain and Odor Remover | 32 Ounces. This stain and odor remover removes tough pet stains like vomit, feces and blood. It doesn’t contain any harsh chemicals and helps remove the pheromones to prevent repeat spritzes.

Key Features

OUT! Advanced Stain and Odor Remover works well on both carpet and wood floors and has enzymes for killing odors. A little goes a long way so it doesn’t require repeated treatments. It may leave an unusual residue behind on some surfaces.

Pros
  • 3-in-1 sprayer
Cons
  • Might have to apply liberally to remove scent
4

Simple Solution Pet Stain and Odor Eliminator

– Best Budget
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THE SCOOP

The bacteria in the solution eat the stain until it biodegrades and evaporates, restoring your surface to its original, clean state. Moreover, the odor left behind by your pet is completely eliminated, discouraging them from urinating or pooping in the same spot. 

Key Features

With 30 years in the business, Simple Solution offers this convenient cleanup spray with a nozzle that can scatter the solution in three ways: mist to cover surface stains and large areas, stream to clean crevices, or foam to apply over embedded or thick messes. The 32-ounce sprayer can be used on fabrics and upholstery.

Pros
  • Three-in-one nozzle sprayer Works on upholstery, fabric Budget-friendly
Cons
  • There’s a different product for tiles, marble, and concrete
5

Amaziing Solutions Pet Stain and Odor Eliminator

– Best Quality
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THE SCOOP

You can get rid of pet odors or stains left on upholstery, carpets, drapes, car interiors, litter boxes, or cat and dog beds using the 32-ounce Amaziing Solutions Pet Stain and Odor Remover.

Key Features

While affected surface areas can be deodorized in five to ten minutes, tougher stains and smells—particularly those left on a carpet—can be removed by soaking it in this non-foamy “bio-enzymic solution” for an hour before drying and vacuuming. No scrubbing is required. Amaziing Solutions are also certificatied by the Carpet and Rug Institute (CRI) as “Green Certified Cleaning Solutions.”

 
Pros
  • CRI-recognized Deep cleaning Citrus scent
Cons
  • Expensive
6

BUBBAS ROWDY FRIENDS Pet Stain and Odor Eliminator

– Best Multiple Uses
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THE SCOOP

Just like Amaziing Solutions, Bubba’s is listed among CRI’s “Green Certified Cleaning Solutions.” It’s also useful as a shoe odor remover, upholstery cleaner, and laundry stain pre-treatment solution.

Key Features

The dormant bacteria in Bubba’s enzyme cleaner makes it last longer than most odor enzyme sprays, which usually only contain active bacteria that slowly die off and lose effect from the time it gets out of the factory. Bubba’s enzymes only activate when introduced to organic food sources such as feces, urine, vomit, or even human waste. The gallon-size “Terminator” can even remove old stains from pets and litter box odors.

 
Pros
  • Dormant bacteria
  • Gentle on skin, can be used for laundry
  • Versatility
Cons
  • No sprayer
Melissa Bartholomew
By Melissa Bartholomew
Melissa is a clinical pharmacist licensed for practice in multiple US states. Her expertise stems from her near-decade long experience in the industry. Melissa began her pharmacy journey with her undergraduate biology and chemistry degrees, and later went on to earn her doctorate in pharmaceutical and health sciences. When she is not working, she is spending time with her children and furthering her passion for wellness.
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